Characteristic | Description |
---|---|
Active Ingredients | Tadalafil 20mg, Dapoxetine 60mg |
Indications | Erectile Dysfunction, Premature Ejaculation |
Onset of Action | 30-60 minutes |
Duration | Up to 36 hours for Tadalafil |
Visit Tadapox Site |
Pharmacokinetics of Tadapox
The Tadapox 20mg/60mg combines Tadalafil and Dapoxetine. Tadalafil has a half-life of around 17.5 hours. It reaches peak plasma concentration between two and four hours after oral ingestion. Dapoxetine is rapidly absorbed, reaching maximum plasma levels in about 1-2 hours. Its half-life is approximately 19 hours. This pharmacokinetic profile aids in long-lasting efficacy.
Tadalafil is mainly metabolized by CYP3A4 enzymes. Its inactive metabolites are excreted primarily via feces and to a lesser extent via urine. Dapoxetine undergoes extensive hepatic metabolism, also predominantly by CYP2D6 and CYP3A4. The metabolites are excreted mainly in urine. Both active substances have minimal impact on hepatic cytochromes, reducing drug-drug interaction risks.
Plasma protein binding is high for both components, which ensures stability within the bloodstream. Tadalafil binds approximately 94%, while Dapoxetine binds 99%. This stability allows Tadapox to maintain therapeutic levels for extended periods.
Mechanism of Action
Tadapox harnesses the synergistic effects of its components. Tadalafil acts as a phosphodiesterase type 5 inhibitor. This action promotes smooth muscle relaxation in the corpus cavernosum, enhancing blood flow and facilitating erection during sexual stimulation. Tadalafil’s effect on blood vessels ensures prolonged sexual readiness.
Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), targets premature ejaculation. It enhances serotonin’s action at synapses, prolonging the time to ejaculation. This action increases control over ejaculation and enhances sexual satisfaction.
The dual-action of Tadapox addresses two prevalent sexual dysfunctions, offering a holistic solution. Both components work independently within their mechanisms, ensuring the simultaneous treatment of erectile dysfunction and premature ejaculation.
Who Can and Cannot Take Tadapox
Tadapox 20mg/60mg is prescribed for adult men experiencing erectile dysfunction and premature ejaculation. It is recommended for those who can benefit from the combined effects of Tadalafil and Dapoxetine. Individuals with underlying health conditions should consult healthcare providers before use.
Contraindications include severe cardiovascular disorders, recent stroke or heart attack, and severe liver impairment. Caution is advised for patients with retinitis pigmentosa or peptic ulcer disease. Men advised against sexual activity due to health reasons should avoid Tadapox.
The use of Tadapox is not intended for women, children, or adolescents under 18 years. Patients taking nitrates or nitric oxide donors must not use Tadapox due to the risk of a serious drop in blood pressure. Interactions with other medications should be discussed with healthcare professionals.
Missed Dose
If a dose of Tadapox is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose. In such cases, the missed dose should be skipped, and the regular dosing schedule resumed.
Taking more than the recommended dose within a 24-hour period increases the risk of adverse reactions without improving efficacy. Consistency in administration enhances effectiveness and minimizes the risk of side effects.
For as-needed use, taking Tadapox prior to anticipated sexual activity suffices. The regimen should be followed as prescribed, considering individual response and tolerability.
Adverse Effects
Common side effects of Tadapox 20mg/60mg include headache, flushing, and nasal congestion. These are typically mild and transient. Gastrointestinal disturbances like nausea and diarrhea may occur, usually resolving with continued use.
Rare but serious adverse events include changes in vision, sudden hearing loss, or an erection lasting more than four hours. Immediate medical attention is essential for these reactions.
Hypersensitivity reactions may manifest as rash or swelling. Patients should be advised to discontinue use if such symptoms appear. Monitoring by healthcare professionals ensures safe use.
Purchasing Tadapox Without a Prescription
Access to Tadapox without a prescription poses risks. Medications obtained without professional guidance may not suit individual health profiles. Prescriptions ensure appropriate dosing and consideration of contraindications.
Counterfeit medications sold online may lack the intended active ingredients, leading to inefficacy or harm. Trusted sources and medical advice are crucial for safe pharmaceutical use.
Key factors in obtaining medications include verifying the legitimacy of sources and consulting healthcare professionals. Ensuring medication safety involves vigilance and adherence to prescribed guidelines.
When purchasing pharmaceuticals, choose licensed pharmacies that require prescriptions. This ensures the quality and safety of medications and contributes to optimal treatment outcomes.
- Always consult healthcare professionals before starting any new medication.
- Verify the legitimacy of online pharmacies.
- Avoid taking multiple medications without guidance.
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